ABSTRACT
We report 3 cases of Visceral leishmaniasis, who presented with unusual clinical manifestations. One child was diagnosed as hemophagocytic syndrome; another masqueraded with features of leukemoid changes alongwith hemophagocytosis and trilineage myelodysplasia; the third case presented with pyothorax. All the three patients showed amastigote forms of Leishmania donovani and positive serology (rk39 antigen). They showed complete clinical, hematological and parasitological resolution with Amphotericin B therapy.
Subject(s)
Amphotericin B/therapeutic use , Antiprotozoal Agents/therapeutic use , Child , Diagnosis, Differential , Humans , Leishmaniasis, Visceral/diagnosis , Leishmaniasis, Visceral/drug therapy , Leishmaniasis, Visceral/complications , MaleABSTRACT
Fine needle aspiration cytology (FNAC) was done on 150 patients with swelling in the head and neck region, during the period of 18 months from July 1994 to December 1995. Of these, 55 patients underwent surgery permitting a correlation between the histopathological diagnosis based on permanent paraffin sections and the diagnosis made by FNAC in order to evaluate FNAC in terms of accuracy along with its complications and limitations. The overall accuracy in the 55 cases evaluated was 92.73% with sensitivity of 90.91% and specificity of 93.18%. It was confirmed that FNAC is a highly diagnostic procedure for assessing swellings in the head and neck region. The method is simple, safe and economical.